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Segment-specific but pathologic laminin isoform profiles in human labial salivary glands of patients with Sjögren's syndrome

✍ Scribed by Mikael Laine; Ismo Virtanen; Tuula Salo; Yrjö T. Konttinen


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
419 KB
Volume
50
Category
Article
ISSN
0004-3591

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Overexpression of phosphorylated STAT-1α
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## Abstract ## Objective To clarify the molecular mechanisms of Sjögren's syndrome (SS), we analyzed the functional role of the STAT‐1 gene, one of the interferon‐γ (IFNγ)–inducible genes, in labial salivary glands (LSGs) from SS patients. ## Methods The expression of STAT‐1 messenger RNA (mRNA)