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Sedimentation of single human red blood cells. Differences between normal and glutaraldehyde fixed cells

✍ Scribed by Alfred W. L. Jay; Peter B. Canham

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
455 KB
Volume
80
Category
Article
ISSN
0021-9541

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✦ Synopsis

The sedimentation behaviour of single human red blood cells fixed with glutaraldehyde at p H 7.4 and 6.4 was studied and compared to results previously reported for normal fresh cells. The cells fixed at pH 7.4 were observed to have normal shapes while those fixed at pH 6.4 were more spherical and less disc-like. Fixation of glutaraldehyde removed "membrane flicker," resulting in increased stability as indicated by a decrease in the num-

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