Since European settlement in the early 1800s, 66 artificial meander cut-offs have been created in the lower Latrobe River, Victoria. Contemporary waterway management practices include the reinstatement of a selection of these cut-off meanders to slow water flows and reduce river bed and bank instability. Infill sediments were collected from a range of depths from one of these meanders prior to its reinstatement to estimate the potential for remobilization of any sediment pollutants into the waterway. The characteristics of collected sediments were described and sediments were analysed for a range of pollutants including heavy metals, total petroleum hydrocarbons, monoaromatic hydrocarbons, organochlorine pesticides, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs). Metal concentrations in the fine (<63 pm) sediment fraction increased with increasing sample depth; however, only increases in cadmium, chromium and mercury concentrations were statistically significant. Statistically significant increases in mercury concentrations with depth were also present in the entire sediment fraction. With the exception of mercury, concentrations of all metals assessed in meander sediments were similar to those reported as being at background concentrations. Mercury concentrations, although elevated, were below concentrations reported to adversely effect riverine biota. Concentrations of organochlorine pesticides, polychlorinated biphenyls, total petroleum hydrocarbons, monoaromatic hydrocarbons and polycyclic aromatic hydrocarbons were all below detection limits in the entire sediment fraction. As a consequence, reinstatement of the meander as part of a waterway management programme is unlikely to release significant quantities of sediment-partitioned pollutants into the mainstream waterway.