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Secretory expression of all 16 subtypes of the hemagglutinin 1 protein of influenza A virus in insect cells

✍ Scribed by Shujuan Cui; Chao Wu; Hongli Zhou; Rongmao Zhao; Li Guo; Jianwei Wang; Tao Hung

Book ID
113768757
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
850 KB
Volume
177
Category
Article
ISSN
0166-0934

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Secretory expression of all 16 subtypes
Secretory expression of all 16 subtypes of the hemagglutinin 1 protein of influenza A virus in insect cells
✍ Shujuan Cui; Chao Wu; Hongli Zhou; Rongmao Zhao; Li Guo; Jianwei Wang; Tao Hung πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 850 KB

Influenza viruses are known for their ability to change their antigenic structure and create new viral strains. Hemagglutinin (HA), for which 16 subtypes have been identified, is a major antigenic determinant essential for the pathogenesis of influenza A viruses. To predict and monitor future epidem

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## Abstract The hemagglutinin (HA) of influenza A virus plays an essential role in mediating the entry of the virus into host cells. Here, recombinant full‐length HA5 protein from a H5N1 isolate (A/chicken/hatay/2004(H5N1)) was expressed and purified from the baculovirus‐insect cell system. As expe