Identification of the homeobox protein P
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Xianghuai Lu; George R Beck Jr; Linda C Gilbert; Corinne E Camalier; Nicholas W
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Article
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2010
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American Society for Bone and Mineral Research
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English
β 905 KB
Tumor necrosis factor Ξ± (TNF-Ξ±) promotes bone loss and inhibits bone formation. Osterix (Osx, SP7) is a transcription factor required for osteoblast (OB) differentiation because deletion results in a cartilaginous skeleton. We previously described a TNF suppressor element in the Osx promoter that wa