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Secretion of basogranulin from human basophils in response to IgE-dependent and non-IgE-dependent stimuli

✍ Scribed by Mochizuki, A.; McEuen, A.R.; Buckley, M.G.; Walls, A.F.


Book ID
119491687
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
141 KB
Volume
111
Category
Article
ISSN
1097-6825

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## Abstract In mast cells, basophils, and the RBL‐2H3 tumor mast cell model, crosslinking cell surface IgE‐receptor complexes by multivalent ligands activates a signal transduction pathway that leads to the secretion of histamine, serotonin, and other inflammatory mediators. Receptor crosslinking i