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Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics

✍ Scribed by Kei Yamamoto; Yuki Isogai; Hiroyasu Sato; Yoshitaka Taketomi; Makoto Murakami


Publisher
Springer
Year
2011
Tongue
English
Weight
958 KB
Volume
400
Category
Article
ISSN
1618-2650

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After intracerebral injection, some toxic secreted phospholipases A 2 (sPLA 2 ) can induce epileptic seizures which bases are currently ill known. We undertook the detailed study of the central neurotoxicity of paradoxin (PDX), an analog of taipoxin, in rodents. Since literature strongly suggests a