Secreted frizzled related protein 1 regu
β
Tripti Gaur; Lillian Rich; Christopher J. Lengner; Sadiq Hussain; Brune Trevant;
π
Article
π
2006
π
John Wiley and Sons
π
English
β 510 KB
## Abstract Canonical Wnt signaling (Ξ²βcatenin/TCF) has emerged as a key regulator of skeletogenesis. In this study, chondrogenesis is examined in a mouse model in which the Wnt antagonist secreted frizzled related protein 1 (sFRP1) is nonβfunctional and results in a high bone mass phenotype and ac