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Secondary structure of peptidese: 13. 15N and 13C n.m.r. spectroscopic investigation of the helix stability of poly(l-alanine) in acidic solutions

✍ Scribed by Hans R. Kricheldorf; William E. Hull


Book ID
119069990
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
848 KB
Volume
6
Category
Article
ISSN
0141-8130

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Using 1 -chloro-l-[~~N]nitrosocyclohexane, we have prepared five L-[a-'SN]arnino acids. The stereoselective electophillic hydroxyamination of (S)-acylbornane-l0,2-suftams, followed by ZnO/H+ reduction, and alkaline cleavage of the chiral auxiliary, gave the amino acids in 97.2-99.5 % e.e. By starti