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Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain

โœ Scribed by Jeffrey J. Babon; Shenggen Yao; David P. DeSouza; Christopher F. Harrison; Louis J. Fabri; Edvards Liepinsh; Sergio D. Scrofani; Manuel Baca; Raymond S. Norton


Book ID
111310306
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
412 KB
Volume
272
Category
Article
ISSN
1432-1327

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Chemical shift assignments and secondary
โœ Yu-Sen Wang; Anne F. Frederick; Mary M. Senior; Barbara A. Lyons; Stuart Black; ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 832 KB

The growth factor receptor-bound protein-2 (Grb2) is an adaptor protein that mediates signal transduction pathways. Chemical shift assignments were obtained for the SH2 domain of Grb2 by heteronuclear NMR spectroscopy, employing the uniformly 13C-/15N-enriched protein as well as the protein containi