Secondary reduction in calpain 3 expression in patients with limb girdle muscular dystrophy type 2B and Miyoshi myopathy (primary dysferlinopathies)
โ Scribed by Louise V.B Anderson; Ruth M Harrison; Robert Pogue; Elizabeth Vafiadaki; Christine Pollitt; Keith Davison; Jennifer A Moss; Sharon Keers; Angela Pyle; Pamela J Shaw; Ibrahim Mahjneh; Zohar Argov; Cheryl R Greenberg; Klaus Wrogemann; Tulio Bertorini; Hans H Goebel; Jacques S Beckmann; Rumaisa Bashir; Kate M.D Bushby
- Book ID
- 117669332
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 163 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0960-8966
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We report on the clinical, pathological, and genetic features of 7 patients with limb-girdle muscular dystrophy type 2A (LGMD2A) from three Japanese families. The mean age of onset was 9.7 ยฑ 3.1 years (mean ยฑ SD), and loss of ambulance occurred at 38.5 ยฑ 2.1 years. Muscle atrophy was predominant in