✦ LIBER ✦

Secondary lymphoid malignancy in two children with neuroblastoma

✍ Scribed by Imashuku, Shinsaku; Hibi, Shigeyoshi; Kosaka, Kitaro; Tabata, Yasuhiro; Naya, Mayumi; Hohjo, Makoto; Todo, Shinjiro

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 274 KB
Volume: 27
Category: Article
ISSN: 0098-1532
DOI: 10.1002/(sici)1096-911x(199607)27:1<54::aid-mpo10>3.0.co;2-5

No coin nor oath required. For personal study only.

✦ Synopsis

Secondary lymphoid malignancy, particularly acute lymphoblastic leukemia (ALL), is rare. We report one case of ALL and another case of mediastinal lymphoblastic lymphoma developed after treatment for neuroblastoma. The secondary ALL characterized by short latency period and an 11q23 translocation apparently was induced by etoposide treatment. The pathogenesis of the secondary lymphoma is less certain and may be re-lated to previous treatment with cyclophosphamide and radiotherapy, host susceptibility, or chance occurrence. One child died of progressive lymphoma and the other remains in remission 1 year following allogeneic bone marrow transplantation. Additional studies are needed to determine the risk, pathogenesis, and optimal treatment for secondary lymphoid malignancy.

📜 SIMILAR VOLUMES

Blindness in children with neuroblastoma

✍ Asim F. Belgaumi; William M. Kauffman; Jesse J. Jenkins; Jose Cordoba; Laura C. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB 👁 1 views

## Background: Neuroblastoma is the most common extracranial solid tumor among pediatric patients, and orbital metastatic disease is not uncommon in these children. physical signs as a consequence of orbital metastases, such as proptosis and periorbital ecchymosis, frequently are encountered. howev

Neurodevelopmental anomalies in children

Neurodevelopmental anomalies in children with neuroblastoma

✍ Julie Blatt; Ronald L. Hamilton 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 181 KB 👁 2 views

the embryonal neural crest, with aganglionosis coli and neurofibromatosis type I. The aim of the current study was to test the hypothesis that neuroblastoma is part

Prognosis in black children with neurobl

Prognosis in black children with neuroblastoma

✍ William Dinicola; Nasser Movassaghi; Sanford Leikin 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 1 views

Thirty white and 15 black children with neuroblastoma were compared with respect to survival. Patient age and tumor stage at diagnosis were similar in the two groups, as was duration of symptoms prior to diagnosis. There was no significant difference between the white and black children in regard to

Smooth-muscle antibodies in children wit

Smooth-muscle antibodies in children with neuroblastoma

✍ Dr. Daniela Zauli; Francesco Bianco Bianchi; Tullio Gardelli; Umberto Volta; Mar 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB 👁 1 views

Treatment of lymphoid malignancies in pa

Treatment of lymphoid malignancies in patients with ataxia-telangiectasia

✍ Arush, Myriam Weyl Ben 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 20 KB 👁 2 views

Treatment of lymphoid malignancies in pa

Treatment of lymphoid malignancies in patients with ataxia-telangiectasia

✍ Sandoval, Claudio; Swift, Michael 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 2 views

Background. Patients with ataxia-telangiectasia (A-T) are at an increased risk for developing lymphoid malignancies, yet the appropriate therapy remains unknown. Radiation therapy at conventional doses results in destruction of normal tissue, which has suggested that full-dose chemotherapy might res