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Secondary Deuterium Kinetic Isotope Effects in Enantioselective Hydroborations with (+)-Diisopinocampheylborane

โœ Scribed by Dr. Brian E. Mann; Dr. Peter W. Cutts; Dr. James McKenna; Dr. Jean M. McKenna; Dr. Catriona M. Spencer


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
240 KB
Volume
25
Category
Article
ISSN
0044-8249

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A Secondary ฮฒ Deuterium Kinetic Isotope
โœ Stephen Bornemann; Maria-Elena Theoclitou; Martin Brune; Martin R. Webb; Roger N ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 169 KB

Chorismate synthase (EC 4.6.1.4) is the shikimate pathway enzyme that catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to chorismate. The enzyme reaction is unusual because it involves a trans-1,4 elimination of the C-3 phosphate and the C-6 proR hydrogen and it has an absolute