Clonal abnormalities of the long arm of chromosome 13 were detected in 9 of 54 patients with Burkitt lymphoma-leukemia. All abnormalities involved band 13q34, in three patients as t(1;13). The 13q34 abnormalities are thus the second most frequent secondary chromosomal abnormalities, after those of c
Secondary chromosomal abnormalities predict outcome in pediatric and adult high-stage Burkitt lymphoma
β Scribed by Mihaela Onciu; Ellen Schlette; Yinmei Zhou; Susana C. Raimondi; Francis J. Giles; Hagop M. Kantarjian; L. Jeffrey Medeiros; Raul C. Ribeiro; Ching-Hon Pui; John T. Sandlund
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 162 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0008-543X
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Tumour cell karyotypes from patients with Burkitt lymphoma (BL) or Burkitt's type leukemia (ALL3) were studied for correlation with survival, bone marrow and cerebral spinal fluid involvement (CSF), human immunodeficiency virus (HIV) serology, and for recurrent cytogenetic abnormalities. The record
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