๐”– Bobbio Scriptorium
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Secondary antithyroid action of drugs in relation to structure

โœ Scribed by J. Buxeraud; A. C. Absil; C. Raby


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
324 KB
Volume
73
Category
Article
ISSN
0022-3549

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โœฆ Synopsis


Molecular interactions between iodine and disulfiram, clomethiazole, and tolnaftate were investigated by electron spectroscopy. Iodine forms charge transfer complexes with these molecules, with 1:1 stoichiometry and of the n-sigma type. The formation constants were compared with those obtained with antithyroid molecules. Only disulfiram appears to have any effect on the intrathyroid cycle of iodine.


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