𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Second primary head and neck tumor risk in patients with cervical cancer—SEER data analysis

✍ Scribed by Camille C. Rose Ragin; Emanuela Taioli

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
225 KB
Volume
30
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

Human papillomavirus (HPV) causes >99% of cervical carcinomas and is associated with approximately 25% of head and neck squamous cell carcinomas (HNSCCs). The role of HPV infection in HNSCC development after a first diagnosis of cervical cancer is unknown.

Methods.

Using the National Cancer Institute's Surveillance, Epidemiology, and End Results data, the authors compared the risk of second primary cancer (SPC) HNSCC in patients with cervical cancer with the general population and with females with other primary cancers.

Results.

The lifetime risk of SPC HNSCC for patients with cervical cancer was higher than in the general population (standardized incidence ratio [SIR]: 1.7). When compared with that in females with other cancers, the risk of anogenital and oropharyngeal SPC was in excess, but not of SPC in the oral cavity.

Conclusion.

Patients with cervical cancer develop an excess SPC HNSCC in comparison with females with other cancers. A possible role of HPV is suggested. © 2007 Wiley Periodicals, Inc. Head Neck, 2008

📜 SIMILAR VOLUMES

Risk of second primary cancer among pati
Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries
✍ Shu-Chun Chuang; Ghislaine Scelo; Jon M. Tonita; Sharon Tamaro; Jon G. Jonasson; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 186 KB 👁 2 views

## Abstract The objective of the study was to assess the risk of second primary cancers (SPCs) following a primary head and neck cancer (oral cavity, pharynx and larynx) and the risk of head and neck cancer as a SPC. The present investigation is a multicenter study from 13 population‐based cancer r

Risk of third and fourth tumors in patie
Risk of third and fourth tumors in patients with head and neck cancer
✍ Xavier León; Vicenç Martínez; Montserrat López; Jacinto García; Miquel Quer 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB 👁 2 views

## Abstract ## Background The objective of our study was to analyze the incidence and location of second and subsequent tumors in patients after an index head and neck carcinoma. ## Methods A retrospective study was made by reviewing clinical data prospectively collected from 3631 patients with

Synchronous second primary tumors in 2,0
Synchronous second primary tumors in 2,016 head and neck cancer patients: Role of symptom-directed panendoscopy
✍ Erlend Rennemo; Ulf Zätterström; Morten Boysen 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 382 KB

## Abstract ## Objectives/Hypothesis: Second primary tumors (SPTs) are prevalent in head and neck cancer patients. Synchronous SPTs occur within the first 6 months after diagnosis of a first primary tumor. Work‐up of first primary head and neck cancers may include panendoscopy if SPTs are suspecte

Human leukocyte antigens and immunoglobu
Human leukocyte antigens and immunoglobulin allotypes in head and neck cancer patients with and without multiple primary tumors
✍ Nico De Vries; Hemmo A. Drexhage; Leo P. De Waal; Gerda De Lange; Gordon B. Snow 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB 👁 2 views

Human leukocyte antigens (HLA) and immunoglobulin (Ig) allotypes were examined in 98 patients with single head and neck cancers, and in 51 patients with multiple primary tumors. Immunoglobulin allotype Km (1) was present in 4% of patients with multiple primary tumors versus 21% in patients with a si