Second look laparotomy and ovarian cancer
β Scribed by Sean Kehoe
- Book ID
- 102442044
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 59 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
I read with interest the report by Zorlu et al. that effects on quality of life need addressing. The assessment appeared in the April 1994 issue of the Journal of Surgi-of response to new therapeutic modalities remains one cal Oncology on the use of second look laparotomy (SLL) area where SLL could be justified, and hence SLL should in ovarian cancer management { 1). I agree with their be retained for research purposes. Otherwise, SLL cannot comments that SLL will detect disease when other meth-be indicated. ods fail, but stating that SLL still plays a significant role in the management of ovarian cancer in patients with Stages 11, 111, and IV disease must be questioned. Exposing patients with malignancy to a second laparotomy should be carefully considered and the information accrued used to influence therapy and outcome. All patients in the study were exposed to six cycles of platin-based therapy, and presently no other effective treatment is available for those with residual disease (with the possible exception of Taxol). Although the authors state that individual cases may justify SLL, randomised trials have not proven a survival benefit with SLL (2,3), and the I .
π SIMILAR VOLUMES
Between 1973 and 1985, 118 patients in clinical remission after initial surgery and postoperative chemotherapy for epithelial ovarian carcinoma underwent second-look laparotomy at the University of North CaroIim. No evidence of disease (NED) was found in 57 of these patients; 43 patients received 15
Prognosticators of outcome at second-look laparotomy (SLL) were evaluated in 49 patients with epithelial ovarian carcinoma undergoing SLL. Residual tumor volume was found to be the most significant prognosticator of outcome, with initial tumor stage being of secondary importance. Grade of tumor play