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Second-line chemotherapy with irinotecan plus cisplatin after the failure of S-1 monotherapy for advanced gastric cancer

✍ Scribed by Daisuke Takahari; Yasuhiro Shimada; Shigeyuki Takeshita; Hitoshi Nishitani; Atsuo Takashima; Natsuko Okita; Yoshinori Hirashima; Ken Kato; Tetsuya Hamaguchi; Yasuhide Yamada; Kuniaki Shirao

Publisher: Springer
Year: 2010
Tongue: English
Weight: 156 KB
Volume: 13
Category: Article
ISSN: 1436-3291
DOI: 10.1007/s10120-010-0557-0

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## Abstract A phase III trial of S‐1 plus cisplatin (SP) __versus__ S‐1 alone, for first‐line treatment of advanced gastric cancer (SPIRITS trial), has shown that overall survival was better in patients treated with SP than with S‐1 alone. In the present retrospective biomarker study, we aimed to d