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Second-element turn-on of gene expression in an IS1 insertion mutant

✍ Scribed by Schwartz, Edward ;Herberger, Claudia ;Rak, Bodo


Book ID
104725193
Publisher
Springer
Year
1988
Tongue
English
Weight
949 KB
Volume
211
Category
Article
ISSN
0026-8925

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Presence of insertion element IS1 within an operon leads to absence of expression of genes distal to its integration site. This strong polar effect is observed irrespective of the orientation of IS1. Here I report on a mutant of E. coli K12 which allows turn-on of genes located distally to IS1. This