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Sebaceous carcinomas of the ocular adnexa and the Muir-Torre syndrome

✍ Scribed by Cohen, Philip R.

Book ID
122409693
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
376 KB
Volume
27
Category
Article
ISSN
1097-6787

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Different genetic pathways in the develo
Different genetic pathways in the development of periocular sebaceous gland carcinomas in presumptive Muir-Torre syndrome patients
✍ M. Goldberg; C. Rummelt; S. Foja; L.M. Holbach; W.G. Ballhausen πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 400 KB

Periocular sebaceous gland carcinomas (SGCs) occur in the eyelids either sporadically or as a phenotypic feature of Muir-Torre syndrome (MTS). In knockout mice mismatch-repair (MMR) defects or inactivation of the fragile histidine triad (FHIT) gene are associated with MTS-like signs, including SGC.