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Seasonal changes in the antibody responses againstPlasmodium falciparummerozoite surface antigens in areas of differing malaria endemicity in Indonesia

✍ Scribed by Supargiyono, Supargiyono; Bretscher, Michael T; Wijayanti, Mahardika A; Sutanto, Inge; Nugraheni, Dian; Rozqie, Royhan; Kosasih, Ayleen A; Sulistyawati, Sulistyawati; Hawley, William A; Lobo, Neil F; Cook, Jackie; Drakeley, Chris J

Book ID
121586211
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
805 KB
Volume
12
Category
Article
ISSN
1475-2875

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## Abstract The 19 kDa C‐terminal fragment of the malaria parasite merozoite surface protein 1 (MSP1~19~) is a leading malaria vaccine candidate. In rodents, high antibody levels to this protein confer protective immunity, and can be generated by immunization with the antigen in adjuvants. In natur