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Search for potential cholinesterase inhibitors among substituted pyrrolidines and piperazines

โœ Scribed by I. N. Klochkova; N. N. Semenova; A. A. Safonova; M. V. Noritsina


Book ID
105672043
Publisher
Springer
Year
1999
Tongue
English
Weight
293 KB
Volume
33
Category
Article
ISSN
0091-150X

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N-Substituted (3S,4S)-and (3R,4R)-pyrrolidine-3,4-diols 9 and 10, respectively, were derived from ()-land (ร€)-d-tartaric acid, respectively. Compounds 9k, 9l, and 9m with the N-substituents, BnNH(CH 2 ) 2 , 4-PhC 6 H 4 CH 2 NH(CH 2 ) 2 and 4-ClC 6 H 4 CH 2 NH(CH 2 ) 2 , respectively, showed modest i