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Search for genetic variants of the SYNTAXIN 1A (STX1A) gene: the −352 A>T variant in the STX1A promoter associates with impaired glucose metabolism in an Italian obese population

✍ Scribed by Romeo, S; Sentinelli, F; Cavallo, M G; Leonetti, F; Fallarino, M; Mariotti, S; Baroni, M G


Book ID
110046296
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
164 KB
Volume
32
Category
Article
ISSN
1476-5497

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote