Detailed haplotype analysis at the TP53
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Sonia Garritano; Federica Gemignani; Edenir Inez Palmero; Magali Olivier; Ghysla
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Article
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2010
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John Wiley and Sons
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English
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Due to patterns of migration, selection, and population expansion, founder effects are common among humans. In Southern Brazil, a recurrent TP53 mutation, p.R337H, is detected in families with cancer predisposition. We have used whole locus resequencing and high-density single nucleotide polymorphis