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Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cellsin vitro

✍ Scribed by Emmanual Unni, Dimpy Koul, Wai-Kwan Alfred Yung, Raghu Sinha

Book ID: 120699999
Publisher: BioMed Central
Year: 2005
Tongue: English
Weight: 915 KB
Volume: 7
Category: Article
ISSN: 1465-5411
DOI: 10.1186/bcr1276

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## Abstract Methylseleninic acid (MSeA) is a synthetic organoselenium form known to be effective against mammary carcinogenesis __in vivo__. Using the synchronized mouse mammary epithelial tumor cell (TM6) model, we have previously shown that 5 μM MSeA significantly inhibits cell growth and induces