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Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells

✍ Scribed by Jun-Kyu Yeo; Soon-Do Cha; Chi-Heum Cho; Sang-Pyo Kim; Jae-We Cho; Won-Ki Baek; Min-Ho Suh; Taeg Kyu Kwon; Jong-Wook Park; Seong-Il Suh


Book ID
117467341
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
345 KB
Volume
182
Category
Article
ISSN
0304-3835

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## Abstract We have previously reported that interferon‐α (IFNΞ±) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNΞ± and EGF could modulate cell remodeling in our experim