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SDF-1A and hyperoxia synergistically increase circulating endothelial progenitor cells and wound healing in diabetic mice

✍ Scribed by Katherine A. Gallagher; Lee Goldstein; April Nedeau; Haiying Chen; Don Buerk; Jun Lui; Stephen Thom; Omaida Velazquez


Book ID
113677250
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
80 KB
Volume
203
Category
Article
ISSN
1072-7515

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## Abstract Wound healing is impaired in elderly patients with diabetes mellitus. We hypothesized that age‐dependent impairment of cutaneous wound healing in __db__/__db__ diabetic mice: (a) would correlate with reduced expression of the transcription factor hypoxia‐inducible factor 1Ξ± (HIF‐1Ξ±) as