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SDF-1 expression is elevated in chronic human renal allograft rejection

✍ Scribed by U. Hoffmann; B. Banas; B. Krüger; M. Banas; T. Bergler; C. Böger; M. Kammerl; A. Obed; P. Rümmele; S. Segerer; G. A. J. Riegger; B. K. Krämer


Book ID
110889721
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
480 KB
Volume
20
Category
Article
ISSN
0902-0063

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The CD40-CD40L (CD154) interaction plays a pivotal role in the effector mechanisms of allograft rejection. Blockade of the CD40/CD40L costimulatory pathway prevents the development of chronic allograft rejection in several animal transplant models. The relevance of in situ CD40 and CD40L expression