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Screening study for potential lead compounds for natural product-based fungicides: I. Synthesis and in vitro evaluation of coumarins against Botrytis cinerea

✍ Scribed by Mourad Daoubi; Rosa Durán-Patrón; Mohamed Hmamouchi; Rosario Hernández-Galán; Ahmed Benharref; Isidro G Collado


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
123 KB
Volume
60
Category
Article
ISSN
1526-498X

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✦ Synopsis


Abstract

An efficient, one‐pot synthesis of angular and linear dihydropyranocoumarins, along with C‐6 and C‐8 prenylated coumarins is reported. These compounds, together with single‐ and furanocoumarins, were tested for their potential antifungal activity against the phytopathogen Botrytis cinerea Pers ex Fr. The results show that furanocoumarins may be able to control the fungus B cinerea. Copyright © 2004 Society of Chemical Industry