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Screening of the TARDBP gene in familial and sporadic amyotrophic lateral sclerosis patients of Chinese origin

โœ Scribed by Zhang-Yu Zou; Yu Peng; Xin-Ning Wang; Ming-Sheng Liu; Xiao-Guang Li; Li-Ying Cui


Book ID
116781920
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
835 KB
Volume
33
Category
Article
ISSN
0197-4580

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๐Ÿ“œ SIMILAR VOLUMES


High frequency of TARDBP gene mutations
โœ Lucia Corrado; A. Ratti; C. Gellera; E. Buratti; B. Castellotti; Y. Carlomagno; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 183 KB

Recent studies identified rare missense mutations in amyotrophic lateral sclerosis (ALS) patients in the TARDBP gene encoding TAR DNA binding protein (TDP)-43, the major protein of the ubiquitinated inclusions (UBIs) found in affected motor neurons (MNs). The aim of this study was to further define