𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Screening of closantel and rafoxanide in animal muscles by HPLC with fluorescence detection and confirmation using MS

✍ Scribed by Hoi-sze Yeung; Wai-on Lee; Yiu-tung Wong

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
181 KB
Volume
33
Category
Article
ISSN
1615-9306

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A sensitive and selective LC‐FLD method was described for determination of closantel and rafoxanide in bovine and ovine muscles. Bovine and ovine muscles were extracted with ACN and acetone mixture (80:20, v/v). After cleanup with Oasis^®^ MAX SPE cartridges, the sample was analyzed by LC‐FLD using the control point approach. No false‐negative result was observed at or below maximum residue limits and the false‐positive rate was below 5%. Suspected positive sample was confirmed by LC‐MS/MS. This method was suitable for screening of large batch of samples and hence considerably reduced the time and cost required for quantitation and confirmatory analyses.

📜 SIMILAR VOLUMES

Molecularly imprinted polymer for the de
Molecularly imprinted polymer for the determination of trace ractopamine in pork using SPE followed by HPLC with fluorescence detection
✍ Shuo Wang; Li Liu; Guozhen Fang; Chao Zhang; Jinxing He 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

## Abstract In this study, a molecularly imprinted functionalized polymer for the selective separation of ractopamine (RAC) was prepared by combining a surface molecular imprinting technique with a sol–gel method process. The polymer was evaluated by static, kinetic adsorption, and selective experi