Synthesis and screening of a rationally
β
A. CecΓlia A. Roque; M. Γngela Taipa; Christopher R. Lowe
π
Article
π
2005
π
John Wiley and Sons
π
English
β 830 KB
Rational design and combinatorial chemistry were utilized to search for lead protein L (PpL) mimetics for application as affinity ligands for the purification of antibodies and small fragments, such as Fab and scFv, and as potential diagnostic or therapeutic agents. Inspection of the key structural