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Screening of a molecule endowingSaccharomyces cerevisiaewithn-nonane-tolerance from a combinatorial random protein library

✍ Scribed by W. Zou; M. Ueda; A. Tanaka


Book ID
105949083
Publisher
Springer
Year
2002
Tongue
English
Weight
197 KB
Volume
58
Category
Article
ISSN
1432-0614

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Rational design and combinatorial chemistry were utilized to search for lead protein L (PpL) mimetics for application as affinity ligands for the purification of antibodies and small fragments, such as Fab and scFv, and as potential diagnostic or therapeutic agents. Inspection of the key structural