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Screening for trisomies 21, 18 and 13 by cell-free DNA analysis of maternal blood at 10-11 weeks' gestation and the combined test at 11-13 weeks

✍ Scribed by Quezada, M. S.; Gil, M. M.; Francisco, C.; Oròsz, G.; Nicolaides, K. H.


Book ID
126739643
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
110 KB
Volume
45
Category
Article
ISSN
0960-7692

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Screening for trisomy 13 by fetal nuchal
✍ Kevin Spencer; Charas Ong; Hara Skentou; Adolfo W. Liao; Kypros H. Nicolaides 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 78 KB 👁 1 views

In 42 cases of trisomy 13 at 10±14 weeks of gestation, compared with 947 controls, the median multiple of the median (MoM) of maternal serum free b-human chorionic gonadotrophin (b-hCG) and pregnancy associated plasma protein A (PAPP-A) was signi®cantly decreased (0.506 MoM and 0.248 MoM respectivel