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Screening for the mitochondrial DNA A3243G mutation in children with insulin-dependent diabetes mellitus

โœ Scribed by Maria Mylene Abad; Philip D. Cotter; Flora H. Fodor; Signe Larson; Fredda Ginsberg-Fellner; Robert J. Desnick; Jose E. Abdenur


Book ID
117180259
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
849 KB
Volume
46
Category
Article
ISSN
1532-8600

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The mitochondrial tRNALeu(UUR) A to G 32
โœ Smith, P.R.; Dronsfield, M.J.; Mijovic, C.H.; Hattersley, A.T.; Yeung, V.T.F.; C ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 102 KB ๐Ÿ‘ 2 views

The mitochondrial DNA tRNA Leu(UUR) A to G 3243 mutation is associated with maternally inherited diabetes in Caucasians and Japanese. In a Hong Kong Chinese population we have detected the 3243 mutation in 2 of 74 unrelated subjects with well characterized insulin-dependent (Type 1) diabetes mellitu