The synthesis of brain glutamate requires an amino group donor that is efficiently transported into the brain and that is readily transaminated. The branchedchain amino acids (BCAA), particularly leucine, play this important role. The uptake of leucine across the blood-brain barrier is faster than a
โฆ LIBER โฆ
Screening for defects of branched-chain amino acid metabolism
โ Scribed by K. Michael Gibson; Carol F. Lee; Georg F. Hoffmann
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 619 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
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After careful analysis of the literature, Eriksson and Conn (1) concluded that branched-chain amino acid (BCAA) therapy does not appear to significantly affect the prognosis of patients with acute hepatic encephalopathy (HE). In a metanalysis of almost the same studies, Naylor et al. (2) reached the