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Screening and identification of inhibitors against influenza A virus from a US drug collection of 1280 drugs

✍ Scribed by An, Liwei; Liu, Rui; Tang, Wei; Wu, Jian-Guo; Chen, Xulin


Book ID
125417148
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
877 KB
Volume
109
Category
Article
ISSN
0166-3542

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## Abstract __A discovery strategy relying on the identification of fragments through resolution of a constitutional dynamic system, coupled to subsequent static ligand design and optimization, is demonstrated. The strategic design and synthesis of the best molecular fragments identified from a dyn