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Screen magnifiers: evolution and evaluation

✍ Scribed by Blenkhorn, P.; Evans, G.; King, A.; Hastuti Kurniawan, S.; Sutcliffe, A.


Book ID
117889637
Publisher
IEEE
Year
2003
Tongue
English
Weight
512 KB
Volume
23
Category
Article
ISSN
0272-1716

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Overexpressed proteins are often insoluble, and can be recalcitrant to conventional solubilization techniques such as refolding. Directed evolution methods, in which protein diversity libraries are screened for soluble variants, offer an alternative route to obtaining soluble proteins. Recently, sev