Scrapie and the sheep MHC: claims of linkage refuted

✍ Scribed by P. R. Cullen

• Book ID: 104747299
• Publisher: Springer-Verlag
• Year: 1989
• Tongue: English
• Weight: 243 KB
• Volume: 29
• Category: Article
• ISSN: 0093-7711
• DOI: 10.1007/bf00375873

✦ Synopsis

Serapie and the sheep MHC: claims of linkage refuted

Dear Sir, In a recent paper in Immunogenetics (Millot et al. 1988) on the relationship between scrapie and the ovine major histocompatibility complex (OLA), Dr. Millot and his colleagues claim to have shown genetic linkage between scrapie pathogenesis and certain OLA class I haplotypes in a flock of Ile-de-France sheep. Their essential finding is that because the haplotype OLA-A4, B6 was found more