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SCORPION2: A database for structure–function analysis of scorpion toxins

✍ Scribed by Paul T.J. Tan; Anitha Veeramani; Kellathur N. Srinivasan; Shoba Ranganathan; Vladimir Brusic


Book ID
116921508
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
246 KB
Volume
47
Category
Article
ISSN
0041-0101

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Lq2 is a unique scorpion toxin. Acting from the extracellular side, Lq2 blocks the ion conduction pore in not only the voltage-and Ca 2؉ -activated channels, but also the inward-rectifier K ؉ channels. This finding argues that the threedimensional structures of the pores in these K ؉ channels are si