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Scopolamine impairs behavioural function and arginine metabolism in the rat dentate gyrus

✍ Scribed by Logan T. Knox; Yu Jing; Michael S. Fleete; Nicola D. Collie; Hu Zhang; Ping Liu

Book ID: 116785829
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 960 KB
Volume: 61
Category: Article
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2011.08.042

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## Abstract Thyroid hormone activates extracellular signal‐regulated kinases (ERK1 and ERK2), which are important in late long‐term potentiation (L‐LTP). The aim of this study was to determine the possible mechanism underlying the impairment of L‐LTP as a result of hypothyroidism. We investigated t