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Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties

✍ Scribed by Parvez Hakim; Iman S. Gurung; Thomas H. Pedersen; Rosemary Thresher; Nicola Brice; Jason Lawrence; Andrew A. Grace; Christopher L.-H. Huang

Book ID
113843505
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
711 KB
Volume
98
Category
Article
ISSN
0079-6107

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## Abstract Carboxypeptidase E (CPE) is involved in maturation of neuropeptides and sorting of brain‐derived neurotrophic factor (BDNF) to the regulated pathway for activity‐dependent secretion from CNS neurons. CPE knockout (CPE‐KO) mice have many neurological deficits, including deficits in learn