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Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta

✍ Scribed by Sinder, Benjamin P; Eddy, Mary M; Ominsky, Michael S; Caird, Michelle S; Marini, Joan C; Kozloff, Kenneth M


Book ID
118762384
Publisher
American Society for Bone and Mineral Research
Year
2012
Tongue
English
Weight
766 KB
Volume
28
Category
Article
ISSN
0884-0431

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## Abstract Currently, the standard treatment for osteogenesis imperfecta (OI) is bisphosphonate therapy. Recent studies, however, have shown delayed healing of osteotomies in a subset of OI patients treated with such agents. The current study sought to determine the effects of another therapy, RAN