Delayed loss of small dorsal root gangli
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Tandrup, Trine; Woolf, Clifford J.; Coggeshall, Richard E.
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Article
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2000
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John Wiley and Sons
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English
β 157 KB
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The present study deals with changes in numbers and sizes of primary afferent neurons (dorsal root ganglion [DRG] cells) after sciatic nerve transection. We find that this lesion in adult rats leads to death of some DRG cells by 8 weeks and 37% by 32 weeks after the lesion. The loss of cells appears