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Sciatic nerve transection produces death of dorsal root ganglion cells and reversible loss of substance P in spinal cord

✍ Scribed by A. Tessler; B.T. Himes; N.R. Krieger; M. Murray; M.E. Goldberger


Book ID
118870495
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
905 KB
Volume
332
Category
Article
ISSN
0006-8993

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The present study deals with changes in numbers and sizes of primary afferent neurons (dorsal root ganglion [DRG] cells) after sciatic nerve transection. We find that this lesion in adult rats leads to death of some DRG cells by 8 weeks and 37% by 32 weeks after the lesion. The loss of cells appears

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