Prolonged duration local anesthesia with
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Gaia Colombo; Robert Padera; Robert Langer; Daniel S. Kohane
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Article
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2005
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John Wiley and Sons
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English
⚖ 399 KB
## Abstract Glucocorticoids prolong block duration from polymeric microspheres containing bupivacaine, but not from unencapsulated drug. Here we investigate this effect applies to particles with much more rapid drug release and improved long‐term biocompatibility. Male Sprague‐Dawley rats were give