Schnyder's crystalline dystrophy of the cornea
β Scribed by Peter G. Swann; Kel D. Cameron
- Book ID
- 103973266
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 158 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0953-4431
No coin nor oath required. For personal study only.
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## Abstract Schnyder crystalline corneal dystrophy (SCCD) is a rare autosomal dominant disease characterized by progressive corneal opacification resulting from abnormal deposition of cholesterol and phospholipids. Recently, six different mutations on the __UBIAD1__ gene on chromosome 1p36 were fou
Whitish dots in the stroma of the cornea resembling the cloudy dystrophy were observed in 4 patients wearing HEMA contact lenses; a lattice-like corneal pattern was seen in another patient wearing HEMA contact lenses. There were no complaints. Visual acuity was normal. Corneal sensitivity was normal
Schnyder corneal crystalline dystrophy (SCCD) comprises corneal opacities often associated with precocious arcus senilis and genua valga. The metabolic defect seems to be related to abnormal lipid storage in the central part of the cornea, especially the anterior stroma, consisting mainly of noneste