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Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens

โœ Scribed by N. R. Swerdlow; D. L. Braff; V. L. Masten; M. A. Geyer


Publisher
Springer
Year
1990
Tongue
English
Weight
961 KB
Volume
101
Category
Article
ISSN
0033-3158

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Dopamine infused persistently (25 gg/24 h for 13 days) into the nucleus accumbens of rat brain caused phasic increases in spontaneous locomotor activity during the period of infusion. This phasic responding was prevented by lithium administered throughout the infusion period in divided doses (3 x da