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Schimke immuno-osseous dysplasia: A cell autonomous disorder?

✍ Scribed by Leah I. Elizondo; Cheng Huang; Jennifer L. Northrop; Kimiko Deguchi; Johanna M. Clewing; Dawna L. Armstrong; Cornelius F. Boerkoel


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
472 KB
Volume
140A
Category
Article
ISSN
1552-4825

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Schimke immuno-osseous dysplasia is a rare autosomal recessive disorder that affects primarily bone, T lymphocytes, kidneys, and skin. The patients have a triangular face, broad nasal bridge, bulbous nose tip, small palpebral fissures, short neck, long upper lip, and low hairline. Dental abnormaliti