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Schedule dependent toxicity and efficacy of combined gemcitabine/paclitaxel treatment in mouse adenocarcinoma

โœ Scribed by A. Cividalli, F. Mauro, E. Livdi, F. Ceciarelli, P. Altavista, G. Cruciani, D. Tirindelli Danesi

Book ID
118776850
Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
152 KB
Volume
126
Category
Article
ISSN
1432-1335

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We showed previously that a sequential treatment with doxorubicin (4 hr) followed by paclitaxel (24 hr) (Dox=Pacl) induces a synergistic cytotoxic effect in the BRC-230 breast cancer cell line and in human primary breast cancer cultures. The validity of this experimental finding was confirmed in a c