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Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro

✍ Scribed by Akutsu, M; Furukawa, Y; Tsunoda, S; Izumi, T; Ohmine, K; Kano, Y


Book ID
110055133
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
191 KB
Volume
16
Category
Article
ISSN
0887-6924

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Schedule-dependent in vitro combination
✍ Chun-Ming Tsai; Adi F. Gazdar; Reury-Perng Perng; Barnett S. Kramer πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 French βš– 702 KB

Because of conflicting reports of clinical synergy, we used the tetrazolium-based colorimetric (MTT) assay to test in vitro combination effects of methotrexate (MTX) plus 5fluorouracil (FUra) in 4 schedules on 2 human non-small-cell lung cancer cell lines (adenocarcinoma, NCLH23; bronchioalveolar-ce