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Schedule-dependent interaction between paclitaxel and doxorubicin in human cancer cell lines in vitro

✍ Scribed by M. Akutsu; Y. Kano; S. Tsunoda; K. Suzuki; Y. Yazawa; Y. Miura


Book ID
116166544
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
737 KB
Volume
31
Category
Article
ISSN
0959-8049

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We showed previously that a sequential treatment with doxorubicin (4 hr) followed by paclitaxel (24 hr) (Dox=Pacl) induces a synergistic cytotoxic effect in the BRC-230 breast cancer cell line and in human primary breast cancer cultures. The validity of this experimental finding was confirmed in a c